The 25-year-old recorded an epic five-set victory over Novak Djokovic at the Arthur Ashe Stadium.
Andy won a Grand Slam final at the fifth time of asking, and his brother Jamie has revealed that he is proud of his sibling.
Jamie tweeted: "What a historic night! Tonight Andy achieved his dream. He got the result his talent, dedication and perseverance deserved. So proud of him."
Andy adds his US Open triumph to his Olympic gold medal he claimed earlier this summer.