Dai Young's side have been in dominant for as of late, climbing up to fourth place in the table.
However, victory for Gloucester at Adams Park would see the West Country club leapfrog their opponents.
Meanwhile, the away team have kept the same starting XV that defeated Northampton Saints last weekend.
Wasps: Southwell; Wade, Masi, Bell, Varndell; S Jones, Simpson; Taulafo, Thomas, Swainston; Cannon, Wentzel; Johnson, Jones, Vunipola
Replacements: Lindsay, Payne, Taylor, Rae, Everard, Davies, Robinson, Daly
Gloucester: Cook; Sharples, Tindall, Molenaar, May; Mills, Robson; Wood, Dawidiuk, Harden; Lokotui, James; Savage, Qera, Kalamafoni
Replacements: Britton, Murphy, Y Thomas, Hamilton, Cox, Lewis, Monahan, M Thomas
Sports Mole says: Wasps to maintain their winning form