The 34-year-old was tipped to captain the side in the absence of usual skipper Sam Warburton, but head coach Warren Gatland has opted against picking the Ireland international for the decider.
Alun-Wyn Jones will lead out the new-look tourists side and go head-to-head with Wallabies' captain James Horwill, who has twice been cleared of deliberately stamping on the Lions lock during the first meeting between the two sides.
Lions XV: 15 Leigh Halfpenny. 14 Tommy Bowe, 13 Jonathan Davies, 12 Jamie Roberts, 11 George North, 10 Jonathan Sexton, 9 Mike Phillips, 1 Alex Corbisiero, 2 Richard Hibbard, 3 Adam Jones, 4 Alun-Wyn Jones, 5 Geoff Parling, 6 Dan Lydiate, 7 Sean O'Brien, 8 Toby Faletau.
Replacements: 16 Mako Vunipola, 17 Tom Youngs, 18 Dan Cole, 19 Richie Gray, 20 Justin Tipuric, 21 Conor Murray, 22 Owen Farrell, 23 Manu Tuilagi.