Last time these two sides met, they were Premier League clubs.
This time around three Championship points are up for grabs. Some would argue that they are more important to Owen Coyle's Wigan, who despite being made one of the favourites for promotion, currently sit 14th in the table.
Meanwhile, the visiting R's will have to make do with the absence of Joey Barton, who is suspended after he picked up his fifth yellow card of the campaign last time out against Burnley.
That match at Turf Moor ended in a 2-0 victory for the home side, which in turn was QPR's first league defeat of the season. However, victory against Wigan would see them close the gap on the leaders to two points.
Possible starting lineups:
Wigan: Nicholls; Boyce, Barnett, Rogne, Perch; McManaman, Watson, Gomez, McArthur, Powell; Holt
QPR: Green; Assou-Ekotto, Dunne, Hill, Simpson; Kranjcar, Faurlin, Jenas, Henry, Hoilett; Austin
Sports Mole says: 1-1