They can now close in ever nearer on promotion to the Premier League at the DW Stadium in two days' time.
Pearson could rest some of his key players, with Chris Wood likely to get a start up front after setting up one and scoring the other against Burnley.
The Kiwi should replace Jamie Vardy, who went off injured in the first half at Turf Moor.
Wigan boss Uwe Rosler has seen his side stumble recently, picking up just one point from their last two games.
They're still in the top six and will fancy a late run at the automatic promotion spots with Burnley suffering key injuries just at the wrong time.
The reverse fixture back in September went Leicester's way thanks to goals from Liam Moore and David Nugent.
Possible starting lineups
Wigan : Al Habsi; Boyce, Ramis, Barnett, Beausejour; McManaman, Collison, McArthur, Tunnicliffe; Powell, Maynard
Leicester: Schmeichel; De Laet, Moore, Morgan, Schlupp; Mahrez, Drinkwater, James, Dyer; Nugent, Wood
Sports Mole says: 1-1