The hosts have had a mixed start to their Championship campaign and currently lie in 12th position, while Forest have 10 points from 12 to sit top early on.
Forest boss Billy Davies changed his whole team for the League Cup clash, and could well revert to the team that drew with Watford.
Possible starting lineups
Wigan: Carson; Boyce, Barnett, Perch, Crainey; McCann, McCarthy, McArthur, Beausejour; Fortune, Dicko
Forest: Darlow; Lichaj, Hobbs, Wilson, Cohen; Guedioura; Lansbury, Majewski, Reid; Paterson, Mackie
Sports Mole says: 1-2