The Brazilian only joined Spurs in 2010 from Internacional for a fee believed to be in the region of £8m.
Despite admitting that the 23-year-old is "happy" at White Hart Lane, agent Muhamed Sakic has conceded that a switch to Serie A is a possibility.
"Sandro is happy play at Tottenham and very happy to be in London," Sakic told tuttomercatoweb.
"From what we read in the tabloids, Sandro has already joined Zenit and Anzhi. But it's true that we have had interest in him from many European clubs.
"Sandro could go to Italy next season."
Sandro has scored one goal since signing for Spurs.