Spurs spent £109m on seven new players over the summer, while Gareth Bale left for Real Madrid in a world-record £85m deal.
"The investment that we have made raises expectations in people but what we have to do it create a team that bonds together," Villas-Boas is quoted as saying by Sky Sports News.
"That takes time and we see that our opponents are one step ahead as they have players who have been together for many years; that is an advantage that we don't have.
"Now it is about creating a team that bonds together and assumes the responsibility of winning those titles. This is what we have now and hopefully we can get a good response."
Tottenham return to Premier League action on Saturday when they welcome Norwich City to White Hart Lane.