The home side sit just in the top half of the table but they will be determined to launch towards the top six by claiming maximum points over Betis this weekend.
Meanwhile, Betis will hope to overcome their surprise 2-1 defeat to Granada last week as they bid to edge closer to reigning champions Real Madrid in third place.
Real Betis: WDWWL
Sevilla: Palop; Fazio, Navarro, Spahic, Cala, Maduro; Campana, Navas, Medel, Rakitic; Negredo
Real Betis: Adri; Martinez, Paulao, Perquis, Nelson; Benat, Sevilla, Carlos, Canas; Molina, Castro
Sports Mole says: 1-2