Juve have already faced Fiorentina and Celtic so far this week and Conte has claimed that the hectic schedule could affect his players.
"The players are in good shape, I'll just have to see if anyone needs a rest," Conte told reporters at Friday's press conference.
"The idea is to, more or less, go with the side that has done well in these past two games. But I do fear tiredness – that's why I would have preferred to have had the match scheduled for Sunday."
Conte went on to warn his side that Roma will be a "really difficult" opponent.
"They have a great squad and they'll be really motivated against us," he continued. "Roma have great technical value. They started the season aiming for the top spots, now they've slowed down a bit. But this will be a really difficult game."