Navas has yet to find the net in 22 league appearances so far this term and admitted that it would be a "special" venue to break his duck.
"I've just been unable to score the first," AS quotes Navas as saying. "I have had many chances but it has just not happened.
"It would be nice to score my first one at the Bernabeu; it is a special stadium. I'm good at Madrid, I always have good games and I have scored several times."
Sevilla are struggling this season and find themselves in 11th place in La Liga.