Los Blancos will take on their local rivals Atletico Madrid as they look to win the European Cup for the 10th time in their history.
"We need the right attitude and motivation - that can decide the match," UEFA.com quotes Ramos as saying.
"Motivation has to be there, plus the sacrifice and humility that's brought us here. This is the reward for what we've done this year; now we have to give everything and a bit more.
"It's about going home with your head held high and, if we're motivated, we're going to give Atletico a very hard time. This is a unique opportunity for us."