A run of 15 wins from 17 games saw the Royals earn promotion to the top flight, where they currently sit 19th, a point adrift of safety.
With 10 games of the season remaining, McDermott has said that his side can go on another run of good form to secure survival.
He told Sky Sports News: "I know we are going to finish strong. We generally finish strong. We have players that won a league last year and came from nowhere.
"We have that sort of experience and this is a similar sort of thing for us.
"For us it is a 10-game season now. We know what it's about, we know what is required. We did what we had to do last year and will aim to do what we need to this year."
Reading face relegation rivals Aston Villa on Saturday.