Chris Martin will lead the attack for the Rams, who beat Brighton & Hove Albion 4-1 in the second leg of their playoff semi-final earlier this month, while Craig Bryson has recovered from a back injury to take a place on the bench.
Charlie Austin, who scored both of their goals in the semi-final, starts up front, while on-loan midfielder Ravel Morrison is among the substitutes.
Derby: Grant, Wisdom, Buxton, Keogh, Forsyth, Thorne, Hughes, Hendrick, Russell, Ward, Martin
Subs: Legzdins, Bryson, Sammon, Bamford, Whitbread, Dawkins, Eustace
QPR: Green, Simpson, Dunne, Onuoha, Hill, O'Neil, Barton, Kanjcar, Hoilett, Austin, Doyle
Subs: Traore, Morrison, Suk-Young, Hughes, Henry, Zamora, Murphy
You can follow live coverage of the match with Sports Mole this afternoon.