Hughes's strugglers will welcome playmaker Adel Taarabt back into the squad following a hamstring problem.
Danish defender Daniel Agger is still recovering from a broken rib and will not travel to London.
QPR, who have not won a league match in their last six attempts, will begin the encounter in the relegation zone.
QPR: Kenny; Onuoha, Ferdinand, Hill, Traore; Barton, Derry, Wright-Phillips, Taarabt; Zamora, Cisse
Liverpool: Reina; Kelly, Skrtel, Carragher, Jose Enrique; Henderson, Gerrard, Spearing, Downing; Carroll, Suarez
Sports Mole says: 1-2