Neither side has been in electric form of late and they have fallen behind the second tier's leading trio of Burnley, Leicester City and Queens Park Rangers.
Forest go into the match in fifth place, three places ahead of the Royals, who can leapfrog their opponents with an away victory.
If Nigel Adkins's side pull off an away win, they will put an end to a run of four games without a win.
Hosts Forest are struggling with injuries and manager Billy Davies now knows that captain Chris Cohen is out for the season after damaging his cruciate knee ligaments last weekend.
When these two last met back in the 2011-12 season, the home side won 1-0 in both league meetings.
Possible starting lineups
Forest: Darlow; Lichaj, Hobbs, Lascelles, Jara; Mackie, Lansbury, Chalobah, Abdoun, Majewski, Cox
Reading: McCarthy; Gunter, Pearce, Gorkss, Kelly; Baird, Guthrie, Obita; McCleary, Pogrebnyak, Robson-Kanu
Sports Mole says: 2-2