Meanwhile, Steven Taylor is named among the substitutes following an 11-game absence with a hamstring injury.
Reading have made a total of three changes, with former Fulham defender Stephen Kelly making his debut for the Royals.
Newcastle: Krul; Debuchy, Williamson, Coloccini, Santon; Anita, Cabaye; Shola Ameobi, Marveaux, Gutierrez; Cisse
Subs: Elliot, Perch, S.Taylor, Bigirimana, Obertan, Sammy Ameobi, Ranger
Reading: Federici; Harte, Kelly, Pearce, Mariappa; Leigertwood, Guthrie, McAnuff, McCleary; Kebe, Pogrebnyak
Subs: Gunter, Morrison, Akpan, Karacan, Le Fondre, Hunt