The Dutch head into the match in Sao Paulo knowing that they will finish at the top of Group B if they avoid defeat.
However, Van Gaal believes that Chile will be doing all that they can to beat his team and claim top spot.
"Our main aim in a tournament like this one is to progress from the group stages. Now we want to finish first and that is going to be especially hard against Chile," he told FIFA.com.
"Chile are incredibly intense and very organised. They have a fantastic coach who has convinced his players of the way to face games.
"It's beautiful to see them play. I predict a game with a lot of goalscoring chances, just as, like Spain, Chile is a team extremely anxious to attack. I expect a very balanced game."
Both the Netherlands and Chile have won each of their last four matches in all competitions.