The Lions have picked up just two points from five league games, and manager Steve Lomas is under pressure to deliver three points against the Rams.
New signing Martyn Waghorn is likely to be handed his debut after joining the club on loan from Leicester City.
Derby's solid start to the season was undone in their last match when they were comprehensively beaten by Burnley.
Derby County: WLWWL
Possible starting lineups
Millwall: Forde; Robinson, Shittu, Lowry, Beevers; Bailey, Woolford, Henry, Derry, Chaplow; Waghorn
Derby County: Grant; Forsyth, Keogh, Freeman, Buxton; Bryson, Davies, Ward, Hughes, Martin; Russell
Sports Mole says: 1-2