The Magpies failed to find the back of the net in a goalless draw at St James' Park last week for the first leg, but they have the disadvantage of travelling to Ukraine for the crucial decider.
The North-East outfit are currently lingering above the bottom three of the league table, just four points clear of relegation, which suggests that Pardew could refrain from fielding a full-strength side on Thursday.
Meanwhile, Jonatan Cristaldo is expected to lead the line for the home side for the second-leg encounter.
Possible starting lineups
Metalist: Goryainov; Villagra, Gueye, Torsiglieri, Fininho; Edmar, Torres; Marlos, Cleiton Xavier, Sosa; Cristaldo
Newcastle: Krul; Yanga-Mbiwa, S Taylor, Coloccini, Haidara; Tiote, Cabaye; Obertan, Marveaux, Gutierrez; Cisse
Sports Mole says: 0-1