That win lifted the Whites to 12th, but they now face a different prospect entirely with league leaders United making their way to London.
United also won on Wednesday night to move seven points clear at the top, beating Southampton 2-1.
Martin Jol is likely to stick to a similar lineup that achieved success against West Ham, although Dimitar Berbatov could miss out with a hamstring injury. Bryan Ruiz could move from the wing to the number 10 slot, with Ashkan Dejagah coming into the XI.
Possible starting lineups
Fulham: Schwarzer; Riether, Hughes, Hangeland, Riise; Dejagah, Sidwell, Karagounis, Duff; Ruiz; Rodallega
United: De Gea; Jones, Smalling, Vidic, Evra; Valencia, Anderson, Carrick, Kagawa; Rooney, Van Persie
Sports Mole says: 1-3