However, they are up against a resurgent Villa side who have won their last two matches, including a 1-0 win at Sunderland.
Reports have suggested that Darren Bent could be fit for the hosts, while Nathan Baker may also shake off an ankle problem to make his return.
Chris Smalling is available again for United after recovering from a broken metatarsal and Phil Jones might feature among the substitutes following knee surgery.
Aston Villa: DLLDWW
Man Utd: WWWLWW
Aston Villa: Guzan; Vlaar, Clark, Bennett, Lowton; Ireland, Westwood, Bannan, Albrighton; Agbonlahor, Benteke
Man Utd: De Gea; Rafael, Evans, Ferdinand, Evra; Carrick, Cleverley, Fletcher; Rooney, Van Persie, Hernandez
Sports Mole says: 1-3