The Red Devils took 20 players to Stoke City on Sunday afternoon and the same players will be at Upton Park.
"We have no injuries from Sunday against Stoke. It was a tough game, certainly, but there were no injuries and that is a blessing of course," Ferguson told MUTV.
"We have a good, strong squad. We took 20 players with us to Stoke and those 20 players will go with us again on Wednesday night."
Despite having the same players available, Ferguson has been tipped to make a number of changes to his starting lineup for the Premier League clash against the Hammers.