Roberto Mancini has revealed that he is looking to extend the gap at the top of the table this weekend.
City, who thrashed Spurs 5-1 in this season's reverse fixture, can go eight points clear of the North London side with a win. They can also go six points clear of United if the Red Devils lose to Arsenal in Sunday's late kickoff.
"I think when you play against a top squad like Tottenham, [Manchester] United or Chelsea and you win it, your mentality improves," said Mancini.
"Your feeling is better, your confidence is better. I think that is very important, like when we beat Arsenal at home,
"It is not easy to recover eight points if [Spurs] lose, but everything can happen. We maybe didn't think United could lose at home to Blackburn or at Newcastle. So, for this reason, if you don't take every game 100% it is difficult."
City currently sit top of the league with 51 points from 21 games.