Manchester United manager Louis van Gaal has made nine changes from the side that drew 0-0 with Manchester City on Sunday for tonight's League Cup tie with Middlesbrough.
Academy youngsters James Wilson and Jesse Lingard start in place of Wayne Rooney and Juan Mata, while Andreas Pereira replaces Ander Herrera in midfield.
Memphis Depay returns on the wing in place of Anthony Martial, while Michael Carrick and Marouane Fellaini start in midfield.
Argentina international Sergio Romero returns in goal, while Matteo Darmian and Daley Blind start in defence.
Middlesbrough have made five changes from the side that defeated Wolverhampton Wanderers 3-1 at the weekend, as Kike and Stewart Downing return to the starting XI.
Tomas Meijas replaces Dimi Konstantopoulos in goal, while Ben Gibson and Jack Stephens are also named to start.
Manchester United: Romero; Darmian, Smalling, Blind, Rojo; Carrick, Fellaini, Pereira; Lingard, Wilson, Memphis
Subs: De Gea, Young, Schweinsteiger, Herrera, Mata, Martial, Rooney
Middlesbrough: Mejias; Kalas, Ayala, Gibson, Friend; Leadbitter, Stephens, De Pena; Downing, Kike, Nsue
Subs: Konstantopoulos, Amorebeita, Clayton, Fabbrini, Jackson, Nugent, Zucilini
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