The striker continues to be the subject of tight transfer talks between Real and Manchester City as he prepares for the Copa America in his native Chile.
City are thought to have offered the best monetary deal, but Sanchez is said to favour a move to Spain.
"If Barca want him, they will have to pay his fair price, which is €50m. He is the piece missing in [Pep] Guardiola's puzzle, a player who makes the difference," said Pozzo today.
"You do not have to see it as an expensive transfer, since I am sure Madrid will not win anything next year if Barca sign him. I am sure this alone is enough to justify and pay his price.
"That is the math they should do, besides thinking they will be signing a rising star just 22 years old who will bring many joys for at least a decade."
Pozzo also confirmed that City had made a "more generous offer" for the player than their Spanish rivals.