The Reds look increasingly unlikely to reach a Champions League qualifying spot this season following Monday night's 2-0 defeat to West Bromwich Albion, which placed them 12 points adrift of fourth place in the Premier League table.
In contrast, the Swans head into the match under manager Michael Laudrup on the back of a 4-1 triumph over Queens Park Rangers at the Liberty Stadium, placing them one point ahead of their Merseyside opponents in seventh place.
Despite their strong position in the table, Swansea have only won one away fixture in their last six games, while the Reds need to overcome the disappointment of losing to Zenit St Petersburg in the Europa League on Thursday.
Swansea City: WLDDW
Possible starting lineups
Liverpool: Reina; Johnson, Agger, Skrtel, Enrique; Henderson, Lucas, Gerrard, Downing; Sturrdige, Suarez
Swansea City: Vorm; Rangel, Williams, Monk, Davies; Dyer, De Guzman, Ki, Hernandez, Routledge; Michu
Sports Mole says: 2-1