The Reds will play 10 Premier League games across December and January, and they will be without injured Philippe Coutinho during that time.
Manager Jurgen Klopp made eight changes to his team for Tuesday night's 2-0 victory over Leeds United in the EFL Cup quarter-final at Anfield, and Mignolet believes that it shows how much more strength in depth the club have.
The goalkeeper himself is no longer a regular starter due to Loris Karius moving up to first choice.
"We've got a busy January coming up, but we love that," Mignolet told the club's official website. "Everybody in training is pushing. It's not a lie, it's not a cliche, we're working hard to make sure we're ready when there is an injury or a suspension.
"Along this period in the winter we'll need the whole squad and everybody's shown again that they can step in when needed, and that's very important for the whole club to know."
Liverpool sit second in the Premier League table, one point behind Chelsea after 13 games.