Milan have made an inconsistent start to the season, winning two, drawing two and losing two of their opening six fixtures. Massimiliano Allegri's side ran out winners over Sampdoria last time out thanks to a solitary goal from Valter Birsa.
Juventus come into the match on the back of a 2-2 Champions League draw against Galatasaray in midweek.
Milan were also held to a draw in the same competition by Ajax on Tuesday.
AC Milan: LWDLDW
Possible starting lineups
Juventus: Buffon; Barzagli, Bonucci, Chiellini, Lichtsteiner; Vidal, Pogba, Marchisio, Asamoah, Giovinco; Tevez
AC Milan: Abbiati; Zaccardo, Zapata, Mexes, Constant; Poli, De Jong, Muntari, Montolivo, Robinho; Matri
Sports Mole says: 2-0