It will be the 139th meeting between the two clubs, with Ipswich looking to finally exact revenge on the Canaries for the 4-1 and 5-1 defeats they suffered back in the 2010-11 campaign.
To do so, they will need to halt a three-match winless streak in all competitions that has threatened to negate the impressive start they made by beating Fulham on the opening day.
Defeat after extra time to Crawley Town in the first round of the League Cup was a major disappointment for the Tractor Boys, but Mick McCarthy won't be too dismayed with results since then despite only picking up one point from two games.
A 1-0 defeat to Reading at the Madejski is by no means a humiliating result, while the manner of their 2-2 draw against Birmingham City on Tuesday - which saw Christophe Berra net a 94th-minute equaliser - would have made it almost feel like a win.
Star striker David McGoldrick started that midweek match on the bench as he continues his return from a lengthy injury, but he is expected to be restored to the starting lineup this weekend.
Otherwise, Ipswich could be unchanged for the derby, with Berra looking to keep up his good form following his unlikely brace against Birmingham.
In contrast to Ipswich, Norwich have overcome a slow start to the season and now appear to be in full swing, with back-to-back victories.
The Canaries also showed character to bounce back from a goal in the very first minute against Blackburn Rovers on Tuesday, eventually running out 3-1 victors at Carrow Road.
However, their solitary away match this season yielded a 1-0 defeat at the hands of newly-promoted Wolverhampton Wanderers, and Adams will be hoping for more success on the short trip to Portman Road this weekend.
Adams may opt against throwing them straight into a winning team, however, with any debuts more likely to come off the bench. Lewis Grabban will continue up front, meanwhile, having scored three goals in as many games since his summer move from Bournemouth.
Possible starting lineups
Ipswich: Gerken; Chambers, Smith, Berra, Mings; Anderson, Skuse, Hyam, Tabb; McGoldrick, Murphy
Norwich: Ruddy; Whittaker, Martin, Turner, Bennett; Johnson, Tettey; Redmond, Hoolahan, Lafferty; Grabban
Sports Mole says: 2-2