The Viola face Inter on Sunday evening as they look to secure a European place.
"It's essential that we score first, because otherwise it'll play right into Inter's hands," Cuadrado told La Gazzetta dello Sport.
"Their football is all about sitting back and countering. They get into the box with three passes and tend to score at the first shot.
"Antonio Cassano is so good as he starts out wide on the left and invents assists, but it's a heavy blow for them to have lost Diego Milito."
Fiorentina lie sixth in the Serie A table, five points behind third place.