The Italian side, who had a 3-1 lead from the first leg, had the first chance of the evening. Matos was heading away from goal and shot on the turn from around the penalty spot, but couldn't keep it down.
The home side opened the scoring with just two minutes played in the second half. Josip Ilicic lined up a free kick on the right-hand side about 25 yards from goal and clipped it over the wall and into the corner.
Mario Gomez thought he had doubled Fiorentina's lead after finding the net from Borja Valero's pass, but it was ruled out for offside.