Osman is realistic over the club's hopes of hanging on to Baines and Fellaini, with the 32-year-old braced for bad news when he reports for training on Tuesday morning.
He told The Mirror: "Nobody wants to lose their best players. Every Evertonian is hoping that won't be the case, but we live in the real world and things happen differently than you want them to.
"It's always difficult when you're talking about the money which is being bandied about by the clubs that are interested. Of course, we would survive, though. As with any club, no player is bigger than the club.
"If someone goes, you move on, you adapt, you find new ways of playing without those players. Whatever happens come Monday night or Tuesday morning, we will move on and make ourselves strong."