The Toffees welcome the Latics to Goodison Park looking to reach the semi-finals of the competition for the second consecutive year.
"Everybody has a big motivation for this game," Fellaini told the club's official website. "There is a big chance for Everton and the players.
"Every day the players come in and work hard for this, so I hope we can go to the semi-finals this season."
Everton's last appearance in an FA Cup final came in 2009 when they were beaten 2-1 by Chelsea.