It took just 11 minutes for the first goal to go in, with Pizzi firing low and hard into the bottom corner to give the hosts the lead.
A chance went begging for Depor but it was the visitors who went ahead through Francisco Montanes, who dribbled into the box and dinked over the goalkeeper.
This time it was the hosts who levelled within five minutes as Carlos Marchena finished emphatically after latching on to a loose ball.
The hosts dominated after the break and Aythami came within inches of restoring the advantage as he thumped a header against the post.
Abraham was then dismissed five minutes from the end to compound a bad day at the office, and Depor held on for the win.