A win would see Palace move level on points with their opponents, who are just outside the top half.
However, they will be without Jonathan Parr, who picked up an injury in the FA Cup defeat to Wigan Athletic, while Kagisho Dikgacoi and Jerome Thomas could return. Cameron Jerome is also likely to start in attack.
Meanwhile, the Tigers have failed to win at Selhurst Park since 1986 and lost 1-0 to Norwich City last weekend.
Steve Bruce's men have picked up just four points from their last six matches and need a win to consolidate their position in mid-table.
Robbie Brady is in line to make his first league start since December.
Crystal Palace: LWLDLW
Hull City: DLWLLL
Possible starting lineups
Crystal Palace: Seperoni; Mariappa, Gabiddon, Delaney, Moxey; Puncheon, Ward, Jediank, Bannan; Guedioura, Chamakh
Hull City: McGregor; Mcshane, Davies, Bruce; Elmohamady, Huddlestone, Livermore, Koren, Rosenior; Long, Sagbo
Sports Mole says: 2-1