The 22-year-old impressed in the early part of the season for the Blues, but has not been involved in Jose Mourinho's plans in recent weeks.
"We have signed great players over the summer. We have a squad we are very happy with," Klopp told Deutsche Presseagentur.
"He (Kevin de Bruyne) is actually not one we are after. He is at Chelsea FC and given the size and quality of the Chelsea FC first-team squad it's quite usual he may sometimes miss out on one or two matches."
De Bruyne has also been linked with a return to Werder Bremen, where he spent last season on loan.