John Terry and Marko Marin drop to the bench, while Petr Cech sits out through injury.
Reading have made one change as Jem Karacan comes in for Garath McCleary.
Reading: Federici; Harte, Kelly, Pearce, Mariappa; Leigertwood, Guthrie, Karacan, McAnuff, Kebe; Pogrebnyak
Subs: Taylor, Shorey, Morrison, Akpan, Robson-Kanu, McCleary, Le Fondre
Chelsea: Turnbull; Azpilicueta, Ivanovic, Cahill, Cole; Ramires, Lampard; Oscar, Mata, Bertrand; Torres