The Spanish duo are just two of eight changes made from the team that beat Bolton 2-1 in the League Cup third round on Tuesday.
Meanwhile, Villa have made two changes as they look to return to winning ways following last week's 3-0 loss at home to Arsenal.
Chelsea: Courtois; Ivanovic, Cahill, Terry, Azpilicueta; Matic, Fabregas; Willian, Oscar, Hazard; Costa
Subs: Cech, Zouma, Filipe Luis, Mikel, Schurrle, Remy, Drogba
Aston Villa: Guzan; Hutton, Cissokho, Baker, Senderos; Westwood, Delph, Richardson, Cleverley; Weimann, Agbonlahor
Subs: Given, Clark, Bacuna, Sanchez, N'Zogbia, Grealish, Bent
Follow live text commentary of today's game here on Sports Mole.