City will be without midfielder Bernardo Silva after the Portuguese was handed a one-match ban for a post made on social media.
However, goalkeeper Ederson has provided Guardiola with a much-needed boost after returning to training after a muscle injury - a development which should see the Brazilian stopper replace Claudio Bravo.
A further change could be made at left-back with Benjamin Mendy likely to be preferred to Angelino, who was handed a rare start against Liverpool.
Having remained as an unused substitute against the Merseyside giants, David Silva could take the place of either Rodri or Ilkay Gundogan in midfield.
With Bernardo sitting out the game and Leroy Sane still a couple of months away from recovering from a knee injury, Riyad Mahrez may feature on the right flank.