Last season, Chelsea were the only team to secure an away win against Everton, who have drawn their first three matches of the new season.
The Belgian told the club's website: "The fact they are still looking for their first win definitely makes things harder. Everton away is a hard, difficult game and they have tough defenders in their team.
"They don't have Marouane Fellaini anymore which might change things but we will see. We have to work hard and if we do then hopefully we will get the right result.
"[Compatriot Kevin] Mirallas is very quick and skillful which definitely contributes to him being a threat. He's very good, he can score goals and makes life difficult for defenders."
Chelsea sit second in the Premier League table ahead of today's games.