The League One side are considered even bigger underdogs this afternoon, but Rosler says that it will suit him if his opposite number, Rafa Benitez, decides to rotate his team.
"Since bigger clubs have 11 designated players, there are those who must sit on the bench," Rosler told Goal.com. "It's difficult for them as they have not played for a while and then are thrown in against combative and highly-motivated third-tier players.
"You have seen that we can raise our performance against a team like Chelsea, not individually but the performance of the entire team.
"If you have a good game plan, help yourself and close down space quickly like we did, then you always have a chance, even against Chelsea's world stars."
Brentford face Chelsea at 12pm today.