Burton Albion closed the gap on League Two leaders Wycombe Wanderers to just points by thrashing bottom-of-the-table Hartlepool United 4-0.
Wanderers keep top spot after coming from a goal down to comfortably beat 10-man Southend United 4-1.
Shrewsbury Town fall four points behind the Chairboys after playing out the league's only stalemate this weekend, sharing a point with Cambridge United.
Luton Town's Steve McNulty picked up two yellow cards in as many minutes to assist Morecambe's 3-0 win at home.
Plymouth Argyle move into the playoff places, but suffered a nervy finish, as Northampton Town scored two late goals to nearly salvage a point in a 3-2 defeat.
Newport County's goalscorer Aaron O'Connor picked up a late red card as they beat Stevenage 2-0 at home, while Tranmere Rovers move out of the relegation zone with a 1-0 win over Dagenham & Redbridge.
Tyrone Barnett scored a 90th minute winner as Oxford United come from a goal down to beat Bury 2-1.
Exeter City climb into the playoff places after second-half goals from Scott Bennett and Matt Grimes were enough to beat Carlisle United.
Piero Mingoia scored the winner for Accrington Stanley in their five-goal thriller against Portsmouth. Matt Tubbs kept up his goalscoring form, as he scored the winner for AFC Wimbledon against York City away from home.
Zack Kotwica cancelled out Vadaine Oliver's 55th-minute opener to rescue a point late on for Cheltenham Town against Mansfield Town.
Results in full (half-time scores in brackets): Burton Albion 4-0 Hartlepool United, Cambridge United 0-0 Shrewsbury Town, Dagenham & Redbridge 0-1 Tranmere Rovers, Exeter City 2-0 Carlisle United, Mansfield Town 1-1 Cheltenham Town, Morecambe 3-0 Luton Town, Newport County 2-0 Stevenage, Northampton Town 2-3 Plymouth Argyle, Oxford United 2-1 Bury, Portsmouth 2-3 Accrington Stanley, Wycombe Wanderers 4-1 Southend United, York City 2-3 AFC Wimbledon.
