The Clarets can edge nearer to the playoff places in the Championship table with a win at Turf Moor, while the Blues could move eight points clear from the relegation zone with maximum points.
Birmingham, who have had a stuttered start to the second half of the season, have not managed to claim a win in their last six matches in the league.
For Saturday's encounter, Burnley are likely to line up with a five-man midfield, which could include Chris McCann and Dean Marney, while Birmingham could bring in Nikola Zigic in place of Wade Elliott.
Possible starting lineups
Burnley: Grant; Trippier, Shackell, Edgar, Lafferty; Stanislas, Marney, McCann, Ings, Wallace; Vokes
Birmingham: Butland; Caddis, Caldwell, Davies, Robinson; Burke, Reilly, Gomis; Zigic; Redmond, Hall
Sports Mole says: 1-0