The hosts confirmed their appearance in the playoffs with a solid 2-1 win away to Leeds United, but they are too far away from Watford in third to move up in the table even with victory.
For Wolves it is a must-win game if they are to stand a chance of going above both Peterborough United and Barnsley into 21st.
Possible starting lineups
Brighton: Kuszczak; Bruno, Upson, Greer, Bridge; Lopez, Bridcutt, Orlandi; Buckley, Ulloa, Barnes
Wolves: De Vries; Doherty, Johnson, Gorkss, Robinson; Hunt, Doumbia, Henry, Ward; Dicko, Doyle
Sports Mole says: 2-0