The reverse of this fixture was just under three weeks ago and the two teams couldn't be separated as it ended in a 1-1 draw.
Vicente could earn a start after his match-winning free kick against Hull.
Blackburn manager Michael Appleton is likely to stick with the same side that edged Ipswich on Saturday and have won two on the bounce.
Possible starting lineups
Brighton: Kuszczak; Bruno, El Abd, Upson, Bridge; Vicente, Orlandi, Lopez, Bridcutt; Mackail-Smith, Ulloa
Blackburn: Kean; Orr, Dann, Hanley, Martin Olsson; Pedersen, Lowe, Murphy, Markus Olsson; Kazim-Richards, Rhodes
Sports Mole says: 2-1