The Cherries have surged into the playoff race thanks to their recent run of five wins in the last six games.
They go into Friday's game just two points outside of the top six but three places adrift of the playoffs in what is an extremely tight contest for the fourth and final spot.
Harry Arter remains absent as he is serving the third and final game of a suspension.
Opponents Wednesday, on the other hand, appear to have little to play for in the run-in as they are 10 points clear of the relegation zone and 14 adrift of the playoffs.
The reverse fixture just before Christmas went Bournemouth's way as they came out on top 2-1 at Hillsborough.
Possible starting lineups
Bournemouth: Camp; Francis, Cook, Elphick, Harte; Ritchie, O'Kane, Surman, Fraser; Kermorgant, Grabban
Sheffield Wednesday: Kirkland; Buxton, Onyewu, Llera, Mattock; Coke, Palmer, Lee; Antonio, Nuhiu, Maguire
Sports Mole says: 2-0