The Tangerines have won this fixture on the last two occasions, and have not tasted defeat at home to the Addicks since 1981, when they were in the old Third Division.
Defeat would condemn Powell's men to their fifth defeat of the season - the same number that they racked up in the entirety of their promotion-winning League One campaign last season.
Blackpool: Gilks; Crainey, Evatt, Baptiste, Broadfoot; Robertson, M Phillips, Sylvestre, Martinez; Taylor-Fletcher, Phillips
Charlton: Hamer, Solly, Morrison, Cort, Wilson; Kerkar, Hollands, Stephens, Green, Jackson; Wright-Phillips
Sports Mole says: 2-0