The home side, who currently linger in the relegation zone having taken 10 points, have struggled in defence this season and have conceded 31 goals so far.
A win this weekend could move them out of the bottom three, while visitors Doncaster remain just one point above the relegation spots following a 3-1 defeat to Brighton & Hove Albion last weekend.
Both have secured two wins out of the five times that they have played one another, with one draw. However, Barnsley managed to get the better of Doncaster the last time the two sides met at Oakwell.
Doncaster Rovers: WLWLLL
Possible starting lineups
Barnsley: Butland; Kennedy, Cranie, Wiseman, M'voto; O'Grady, Perkins, Fox, O'Brien, McCourt; O'Grady, Pedersen
Doncaster Rovers: Turnbull; Wabara, Khumalo, McCullough, Jones; Yun, Wellens, Keegan, Copinger; Duffy, Cotterill
Sports Mole says: 1-1