The Dutch winger failed to break into the first team at Camp Nou after his £2.5m arrival two years ago and was loaned out to Schalke 04 last season.
A number of clubs across Europe have been linked with the 27-year-old, but Brands believes that a return to PSV would see him regain his place in the national side.
"There is always a place for him," he told Voetbal International.
"If he wants to come with a view to his recovery and a place in the Oranje, the door is open."
Afellay made 15 appearances for Schalke last season.